Dr. Mills suspects the TRT/semaglutide hype stems from the decades-long practice among bodybuilders of taking metformin in combination with either testosterone or an anabolic steroid. Unlike semaglutide, metformin also isn’t likely to cause a loss of lean muscle tissue. However, Bill might have lost the weight and preserved his muscle even if the semaglutide he bought wasn’t real. The Testosterone Diet gives you enough calories to support muscle growth and testosterone levels without adding bodyfat. Several studies showed that a high-protein diet actually decreased testosterone levels. The best types of exercise to increase your testosterone levels are weightlifting and high-intensity interval training (HIIT). Supplements aren't the only way to increase your testosterone levels naturally. A review of dozens of clinical trials showed that DHEA supplements do increase blood testosterone levels in men and women. Consuming protein and carbs after training has been shown to increase the amount of testosterone that enters muscle cells, where it can increase muscle growth. That’s because research shows that consuming more protein than carbs may lower testosterone levels. In other words, all that testosterone can be put to work to stimulate muscle growth. While we constantly preach the importance of eating protein and make no mistake, it’s vital in The Testosterone Diet what’s even more crucial is getting just enough of it and not too much. Diet can influence the amounts of both active testosterone and estrogens in the blood. Only the free kind can work to increase muscle size by entering the muscle cells. Your nutritional regimen can also influence testosterone after it’s produced. Besides, there’s nothing cute or fancy about building big-time muscle. You also need to use a strong dosage formulated with Labrasol, a delivery technology borrowed from drug companies that increases bioavailability. But he would mix the semaglutide himself, adding sterile water to the powder he purchased from a website—no prescription, medical history, or insurance required. And nothing will stop them from doing it—not a drug shortage or even the possibility of death. Also called androgen replacement therapy, this is a medical treatment your doctor may prescribe if blood tests show unusually low levels of testosterone. More than 33% of men over 45 may have lower than normal testosterone levels. Some older people on testosterone therapy could face increased cardiac risks. Similarly, if I try to bulk beyond, say 25 percent body fat, my body will also fight me by lowering my appetite, boosting my metabolism, sweating like crazy, and so on. It says that instead of a single body fat set point, there are actually two points that each act as a boundary for a set range where our body is most comfortable. Body fat set point theory is the idea that we each have a specific level of body fat that our body will fight to maintain. Your metabolism will peak here, so pair training with precise nutrition (see below) to unveil your leanest, strongest self. You don’t need testosterone replacement therapy (TRT) to fight back. If you’ve hit your 30s or 40s and noticed your metabolism slowing, belly fat creeping in, and workouts not hitting like they used to—you’re not alone. At the same time, Bill understands the temptation. It takes patience and typically requires the help of a doctor, a dietitian, and an exercise physiologist, says Dr. Jaisinghani. While it’s challenging to do both simultaneously, it’s not impossible. Aside from that, she’d prescribe TRT only to a man with clinically low testosterone.